The Washington State cornerback swarmed to the ball from the upper portion of the field to lay a powerful hit on Cenacle. His ...

The San Francisco 49ers and fantasy football managers won't have star wide receiver Brandon Aiyuk at their disposal anytime soon following his knee injury.

Coach Kyle Shanahan said tests Monday confirmed the initial diagnosis Aiyuk tore his ACL and would need major reconstructive ...

KANSAS CITY — The Kansas City Chiefs just keep winning, even as the injuries continue to pile up.

And yet Kyle Shanahan treated it like he treats all games: He played not to lose. So the 49ers lost.

The San Francisco 49ers were hit with a double dose of rough health news regarding two wide receivers on Monday. First, the ...

One of the best runners in the NFL will be on display when Jordan Mason and the San Francisco 49ers host the Dallas Cowboys ...

As the NFL trade deadline looms, the 49ers find themselves in a familiar position—needing to fill gaps left by injuries as they push toward a deep playoff run. With key players like Christian ...

How does every NFL team stack up against each other going into Week 8 with a lot of teams making statement victories in Week ...

NFL on FOX' has been accused of stealing a video from a local reporter and not crediting them for it, while even cropping a ...

The strength of the San Francisco 49ers' offense the past few seasons has been the number of dynamic playmakers that makes it ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee ...