At an up-and-down 3-4, the reigning NFC champion San Francisco 49ers can’t be reliably counted on as a bona fide contender. That makes Brandon Aiyuk’s season-ending knee injury an outright disaster for a Bay Area constellation of football superstars still chasing an elusive Lombardi Trophy.

Jordan Mason lost two short scores to his QB and was shut down by a KC defense allowing the fewest fantasy points to RBs, but he saw almost all the work returning from his shoulder injury. Isaac Guerendo fumbled during one of his two touches, and Mason became the first running back to run for 50 yards against Kansas City this season.