Following the significant losses of players due to injury and illness, including Brandon Aiyuk, San Francisco 49ers head ...

And yet Kyle Shanahan treated it like he treats all games: He played not to lose. So the 49ers lost.

The news around wide receiver Brandon Aiyuk's season-ending knee injury during the San Francisco 49ers' 28-18 loss to the ...

Kyle did something strange after the 49ers lost 28-18 to the Chiefs on Sunday. After his postgame press conference, he walked ...

Finally, it appears that the 49ers have some received some good news from an injury standpoint. On Monday, a day after his ...

San Francisco 49ers head coach Kyle Shanahan told reporters that he would be surprised if star running back Christian ...

The 49ers allowed the Chiefs to rush for 184 yards on 39 attempts, an average of 4.7 yards per carry. They held Patrick ...

Chiefs defenders Justin Reid and Chamarri Conner sandwiched the receiver on a tackle in the waning seconds of the first half.

The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, but they may have lost a ...

According to the AP’s Josh Dubow, it’s the second-most games a 49ers head coach has lost to another head coach without ...